Matsynin V V
Biull Eksp Biol Med. 1982 Nov;94(11):9-12.
Experiments on white rats were made to study the effect of normo- and hyperbaric oxygenation on the total oxygen consumption, its tension in tissues, and the course of oxidative processes in liver mitochondrial preparations from animals exposed to oxygen under positive pressure. It was found that the time of the development of the protective reaction to hyperoxia in the mitochondria was in agreement with the onset of a progressive fall of oxygen tension in the tissues. Experiments with hyperbaric oxygenation in the presence of artificial inhibition or stimulation of the oxidative processes in the body demonstrated a pathogenic relationship between the fall of oxygen tension in the tissues and intensification of its recovery in the mitochondria. The recommendations are given as to the use of the results obtained for the elaboration of more effective regimens of oxygen therapy.
对白鼠进行了实验，以研究常压和高压氧合对总耗氧量、组织中氧张力以及在正压下吸氧的动物肝脏线粒体制剂中氧化过程进程的影响。发现线粒体中对高氧的保护反应出现时间与组织中氧张力逐渐下降的开始时间一致。在人工抑制或刺激体内氧化过程的情况下进行高压氧合实验，证明了组织中氧张力下降与线粒体中氧恢复增强之间存在致病关系。针对利用所获结果制定更有效的氧疗方案给出了建议。
