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从胚胎期移植到正常和白化蝾螈体内的白化眼睛发出的视网膜神经通路。

Retinofugal pathways from albino eyes embryonically transplanted to normal and albino axolotls.

作者信息

Cole J, Dolin R, Fahrner K, Gallenson N, Hall J, Harris W

出版信息

Brain Res. 1982 Nov;281(3):346-9. doi: 10.1016/0165-3806(82)90133-x.

DOI:10.1016/0165-3806(82)90133-x
PMID:7150982
Abstract

Albino axolotl eyes were transplanted embryonically to normal and albino axolotl hosts. The animals were allowed to mature for several months and then their transplanted eyes were injected with tritiated proline. The projections from these albino eyes were compared with those obtained from similar transplants of normally pigmented eyes. Special attention was paid to the crossed and uncrossed components of the projections. No differences were found between normal and albino transplants. These results indicate that abnormal retinofugal crossing, which results from a lack of pigmentation in the mammalian eye, does not occur in the axolotl even when the fraction of retinal cells projecting ipsilaterally is experimentally increased by transplanting supernumerary eyes into embryos.

摘要

白化蝾螈的眼睛在胚胎期被移植到正常和白化蝾螈宿主身上。让这些动物成熟几个月,然后向它们移植的眼睛注射氚标记的脯氨酸。将这些白化眼睛的投射与从正常色素沉着眼睛的类似移植中获得的投射进行比较。特别关注投射的交叉和不交叉成分。正常移植和白化移植之间未发现差异。这些结果表明,哺乳动物眼睛中因色素沉着缺乏而导致的异常视网膜外交叉在蝾螈中不会发生,即使通过将多余的眼睛移植到胚胎中,同侧投射的视网膜细胞比例在实验中增加了。

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1
Retinofugal pathways from albino eyes embryonically transplanted to normal and albino axolotls.从胚胎期移植到正常和白化蝾螈体内的白化眼睛发出的视网膜神经通路。
Brain Res. 1982 Nov;281(3):346-9. doi: 10.1016/0165-3806(82)90133-x.
2
Retinofugal pathways in normal and albino axolotls.
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