Lathers C M
Eur J Pharmacol. 1982 Nov 19;85(2):233-8. doi: 10.1016/0014-2999(82)90473-3.
Methylprednisolone (30 or 50 mg/kg i.v.) was given 30 min prior to acute coronary occlusion of the left anterior descending artery. Neither dose of methylprednisolone exerted any effect on the mean postganglionic cardiac sympathetic nerve discharge prior to coronary occlusion and did not eliminate the nonuniform i.e., increased and/or decreased, neural discharge associated with occlusion-induced arrhythmia. Pretreatment with methylprednisolone did not increase the time to arrhythmia or death and did not decrease the number of cats dying after acute coronary occlusion.
在左冠状动脉前降支急性闭塞前30分钟静脉注射甲泼尼龙（30或50毫克/千克）。在冠状动脉闭塞前，两种剂量的甲泼尼龙均未对节后心脏交感神经平均放电产生任何影响，也未消除与闭塞诱发的心律失常相关的不均匀（即增加和/或减少）神经放电。甲泼尼龙预处理并未增加出现心律失常或死亡的时间，也未减少急性冠状动脉闭塞后死亡猫的数量。
