Scolari F, Harms M, Gilardi S
Dermatologica. 1982 Oct;165(4):355-62.
The effect of thalidomide was investigated in 12 patients with chronic lupus erythematosus resistant to classical treatment (antimalarial drugs, topical steroids). 10 patients were improved and 2 were not sensitive to the treatment. The doses were 100 mg/day for a minimum period of 2 months. With the exception of 1 case, the treatment was well tolerated. The indications of thalidomide in dermatology and the mechanism of action of the drug are briefly discussed.
对12例对传统治疗（抗疟药、外用类固醇）耐药的慢性红斑狼疮患者研究了沙利度胺的疗效。10例患者病情改善，2例对治疗不敏感。剂量为每日100毫克，最短疗程2个月。除1例患者外，治疗耐受性良好。简要讨论了沙利度胺在皮肤科的适应证及药物作用机制。
