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[静息性心绞痛中的复杂性室性心律失常]

[Complicated ventricular arrhythmias in angina at rest].

作者信息

Rizzon P, Scrutinio D, De Toma L, Mangini S, Lagioia R, Accettura D, Mitrotti S, Morrone A, Rizzo U

出版信息

G Ital Cardiol. 1982;12(4):247-54.

PMID:7152174
Abstract

To assess the incidence of serious ventricular arrhythmias (SVA) during transient ischemic attacks (IA), 27 patients with severe angina at rest were submitted to Holter monitoring for a total period of 1344 hours. The recorded IA's were 565. To evaluate the time/relation between SVA and ST segment changes, the IA's complicated by SVA were divided in 2 parts: one for the upstroke and plateau phase of ST changes; Hse other for the period of resolution of ST changes and the first 3 minutes after ST return to baseline. SVA's were found in 12 of the 27 patients (44.4%), but only in 29 of the 565 IA's (5.1%). The recorded arrhythmias consisted of: frequent ventricular premature beats (VPB) (greater than or equal to 5/min) in 8 patients, multifocal VPB in 6, paired VPB in 10, ventricular tachycardia in 5, R on T phenomenon in 2. No correlations were found between the occurrence of SVA during IA and type of ST changes, location of ST changes, occurrence of the same arrhythmias outside the IA's. SVA's were significantly more frequent during IA associated with pain than during silent IA. When considering only IA associated with ST elevation, a relation was found between the occurrence of SVA and amplitude and duration of ST displacement. The same relation was not observed when IA's associated with ST depression were taken in consideration. Among the 29 IA's complicated by SVA, 22 showed the arrhythmias during the first phase (3.8% of all IA's) and 7 during the second phase (1.3% of all IA's); 6 of these 7 IA's were associated with ST elevation.

摘要

为评估短暂性脑缺血发作(IA)期间严重室性心律失常(SVA)的发生率,对27例静息时重度心绞痛患者进行了动态心电图监测,总时长为1344小时。记录到的IA发作有565次。为评估SVA与ST段改变之间的时间/关系,将并发SVA的IA分为两部分:一部分为ST段改变的上升和平台期;另一部分为ST段改变恢复阶段及ST段恢复至基线后的前3分钟。27例患者中有12例(44.4%)出现SVA,但565次IA发作中仅有29次(5.1%)出现SVA。记录到的心律失常包括:8例频发室性早搏(VPB)(≥5次/分钟)、6例多源性VPB、10例成对VPB、5例室性心动过速、2例R波落在T波上现象。IA期间SVA的发生与ST段改变类型、ST段改变部位、IA之外相同心律失常的发生均无相关性。与无痛性IA相比,伴有疼痛的IA期间SVA明显更频繁。仅考虑伴有ST段抬高的IA时,发现SVA的发生与ST段移位的幅度和持续时间有关。考虑伴有ST段压低的IA时未观察到同样的关系。在29例并发SVA的IA中,22例在第一阶段出现心律失常(占所有IA的3.8%),7例在第二阶段出现(占所有IA的1.3%);这7例IA中有6例与ST段抬高有关。

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