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基底细胞癌。一例长期被忽视的病例和一例早期发现的病例。

Basal cell carcinoma. A case of longstanding neglect and a case of early detection.

作者信息

Jones W L

出版信息

J Am Optom Assoc. 1982 Dec;53(12):999-1003.

PMID:7153451
Abstract

The early detection and referral of a small basal cell carcinoma of the face will prevent extensive surgical excision and repair necessary for a neglected lesion. Since these tumors occur in the older population, careful examination of the skin should be performed on patients 50 years of age and older. This cancer has been estimated to constitute 90% of all malignant lid tumors and a suspicious lesion on the lid should be considered a basal cell carcinoma until proven otherwise. The lesion has a very characteristic appearance as described in the text; however, they can present with an atypical picture. An important sign in the evaluation of a possible malignant lid tumor is the loss of eyelashes within or adjacent to the lesion, which indicates the destructive nature of the tumor to the hair follicles. Basal cell carcinomas do not metastasize to distant locations in the body but rather extend locally and can produce deep tissue invasion. Differential diagnosis can present problems to the clinician but the definitive diagnosis is dependent upon the pathologist. The treatment usually requires surgical removal with wide excisional margins; however, other forms of treatment have been attempted. Recurrences of basal cell carcinomas are not uncommon, especially following an initial recurrence and it is mandatory that these patients be re-examined at least every six months for a two year follow-up period.

摘要

面部小基底细胞癌的早期发现和转诊可避免对被忽视病变进行广泛的手术切除和修复。由于这些肿瘤多见于老年人群,应对50岁及以上的患者进行仔细的皮肤检查。据估计,这种癌症占所有眼睑恶性肿瘤的90%,眼睑上的可疑病变在未得到其他证实时应被视为基底细胞癌。如文中所述,该病变具有非常典型的外观;然而,它们也可能呈现非典型表现。评估可能的眼睑恶性肿瘤时的一个重要体征是病变内部或周边睫毛缺失,这表明肿瘤对毛囊具有破坏性。基底细胞癌不会转移至身体其他部位,而是局部扩散并可导致深部组织浸润。鉴别诊断可能给临床医生带来问题,但最终诊断取决于病理学家。治疗通常需要进行广泛切除边缘的手术切除;然而,也尝试过其他治疗方式。基底细胞癌复发并不罕见,尤其是在首次复发后,这些患者必须在至少两年的随访期内每六个月复查一次。

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