Yoshida K
Nihon Seikeigeka Gakkai Zasshi. 1982 Aug;56(8):739-51.
Recently, there has been a tendency to use larger plates such as an AO compression plate in the operative treatment of fractures. However, it was found that the rigid plate fixation for a long period greatly have an effect on the cortex and bone strength. In this regards, the author studied the influences on the cortex and bone strength after long fixation with three types of plates which have large differences in stiffness. Moreover, the rigidity of fracture immobilization was investigated for each plate. The experimental results in mature rabbits as experimental animals showed that the least thinning of the cortex was obtained by use of high density polyethylene (HDP) plate with lowest rigidity and bone strength decreased with increasing rigidity of the plate. However, the fracture site fixed with a HDP plate showed malunion. On the other hand, a carbon fiber polybutylene-telephthalate composite (CFP) plate which has the elastic modulus almost corresponding to that of the tibiofibular bone of a rabbit had less influences on the bone cortex as compared to a stainless steel plate with highest rigidity. Therefore, a CFP plate had less influences on the bone and gave a moderate rigidity in fracture immobilization.
最近，在骨折的手术治疗中出现了使用更大的钢板（如AO加压钢板）的趋势。然而，人们发现长期的刚性钢板固定对皮质骨和骨强度有很大影响。在这方面，作者研究了三种刚度差异很大的钢板长期固定后对皮质骨和骨强度的影响。此外，还研究了每种钢板固定骨折的刚度。以成年兔作为实验动物的实验结果表明，使用刚度最低的高密度聚乙烯（HDP）钢板时皮质骨变薄最少，且骨强度随钢板刚度增加而降低。然而，用HDP钢板固定的骨折部位出现了畸形愈合。另一方面，与刚度最高的不锈钢板相比，弹性模量几乎与兔胫腓骨相当的聚对苯二甲酸丁二醇酯碳纤维复合材料（CFP）钢板对骨皮质的影响较小。因此，CFP钢板对骨的影响较小，且在骨折固定中提供适度的刚度。
