Aubry J P, Aubry M C, Henrion R, Boué J, Labbe F
J Genet Hum. 1982 Oct;30(3):233-53.
Some multisystemic abnormalities associations which can be found by ultrasound examination are sometimes chromosome anomalies and amniocentesis must be performed for confirmation. By ultrasonography we can now reach a new objective element: the fetus extremities. Limbs anomalies, such as polydactily, club-feet and/or club-hands must lead to perform amniocentesis in order to assess or not a possible 13 or 18 trisomy.
超声检查发现的一些多系统异常关联有时是染色体异常,必须进行羊膜穿刺术以确诊。通过超声检查,我们现在可以获得一个新的客观因素:胎儿肢体。肢体异常,如多指畸形、马蹄内翻足和/或畸形手,必须进行羊膜穿刺术以评估是否可能存在13或18三体综合征。