Wakakura M, Ishikawa S
Jpn J Ophthalmol. 1982;26(3):282-91.
Morphological studies were carried out to elucidate whether centrifugal fibers are present in the cat retina. Unilateral optic nerve transection with the minimum vascular damage was performed at 6 mm behind the eyeball via the soft palate approach in adult specific pathogen free cats. Light and electron microscopic observations were performed at 40 and 96 hours after the optic nerve transection. At 40 hours, when there was no evidence of degenerative change in the retinal ganglion cells, degenerative changes were observed in the neuronal processes in the outer part of the inner plexiform layer. Two forms of degeneration occurred in close proximity to the cell bodies or the processes of amacrine cells: electron opaque and electron lucent degeneration. Since degeneration of the ganglion cells became manifest at 96 hours, the early neuronal changes in the inner plexiform layer were thought to represent degeneration of the centrifugal fibers.
进行了形态学研究，以阐明猫视网膜中是否存在离心纤维。在成年无特定病原体的猫中，通过软腭途径在眼球后方6毫米处进行单侧视神经切断术，使血管损伤最小化。在视神经切断术后40小时和96小时进行光镜和电镜观察。在40小时时，视网膜神经节细胞没有退行性变化的迹象，但在内网状层外部的神经元突起中观察到了退行性变化。在无长突细胞的细胞体或突起附近出现了两种退化形式：电子不透明和电子透明退化。由于神经节细胞的退化在96小时时变得明显，因此内网状层早期的神经元变化被认为代表离心纤维的退化。
