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[乙胺碘呋酮对猫心室颤动阈值的影响]

[Effect of cordaron on the threshold of ventricular fibrillation in cats].

作者信息

Stoliarchuk A A, Storozhuk B G

出版信息

Kardiologiia. 1982 Nov;22(11):82-4.

PMID:7154512
Abstract

In an experimental study on cats, cordaron administered in a dose of 5 mg/kg significantly increased ventricular fibrillation threshold. Used in a concentration of 1.5 x 10(-6) g/ml, the drug prevented ventricular fibrillation in an isolated heart which had been caused by reduced content of potassium ions and increased content of calcium ions in the perfusate. This action may be due to its influence on myocardial ion transport.

摘要

在一项针对猫的实验研究中,以5毫克/千克的剂量给予可达龙可显著提高心室颤动阈值。当以1.5×10⁻⁶克/毫升的浓度使用时,该药物可预防因灌注液中钾离子含量降低和钙离子含量增加而导致的离体心脏心室颤动。这种作用可能归因于其对心肌离子转运的影响。

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