Storozhuk B G, Stoliarchuk A A
Farmakol Toksikol. 1980 Sep-Oct;43(5):579-81.
Effect of lidocain, quinidine, ethmozine, cordaron and obsidan on the ventricular fibrillation threshold was studied in experiments on cats with an opened thorax under nembutal anesthesia. The experiments were carried out on normal animals and animals with acute myocardial infarction exposed to isadrin. Lidocain exerted the most pronounced antifibrillar action in all 3 series of experiments. Ethmozine was most active in animals exposed to isadrin.
在戊巴比妥麻醉下对开胸猫进行实验,研究利多卡因、奎尼丁、乙吗噻嗪、胺碘酮和澳苷对心室颤动阈值的影响。实验在正常动物和用异丙肾上腺素造成急性心肌梗死的动物身上进行。在所有3组实验中,利多卡因表现出最显著的抗纤颤作用。乙吗噻嗪在使用异丙肾上腺素的动物中活性最强。