Martimbeau P W, Kjorstad K E, Iversen T
Obstet Gynecol. 1982 Aug;60(2):215-8.
From 1967 through 1972, 562 patients with squamous cell carcinoma of the cervix, stage IB (FIGO), underwent radical hysterectomy with pelvic lymphadenectomy. The patients with pelvic metastases were treated with external beam supervoltage irradiation of 4000 or 5000 rads to the pelvis. Metastases in the pelvic lymph nodes were found in 21.3%. In this study the authors analyzed in detail which nodes were involved with metastases and the relationship with survival and with recurrence. The overall 5-year survival for patients with pelvic lymph node metastases was 53%; for patients without metastases it was 92%. The site of recurrence in patients without demonstrable pelvic lymph node metastases was also examined. The main conclusion drawn from the study is that patients with pelvic node metastases below the common iliac group have a much better prognosis than patients in whom metastases are located in the common iliac nodes; in addition, when nodal involvement is below the common iliac level, patients with disease limited to one node or one group of nodes do not have a better prognosis than patients with multiple metastatic nodes.
1967年至1972年期间，562例国际妇产科联盟（FIGO）分期为IB期的子宫颈鳞状细胞癌患者接受了根治性子宫切除术及盆腔淋巴结清扫术。盆腔转移患者接受盆腔4000或5000拉德的体外高能射线照射。盆腔淋巴结转移率为21.3%。在本研究中，作者详细分析了哪些淋巴结发生转移以及转移与生存和复发的关系。盆腔淋巴结转移患者的总体5年生存率为53%；无转移患者为92%。对无明显盆腔淋巴结转移患者的复发部位也进行了检查。该研究得出的主要结论是，髂总动脉组以下有盆腔淋巴结转移的患者比髂总动脉淋巴结有转移的患者预后好得多；此外，当淋巴结受累在髂总动脉水平以下时，疾病局限于一个淋巴结或一组淋巴结的患者与有多个转移淋巴结的患者相比，预后并无更好。
