Buvat J
Nouv Presse Med. 1982 Nov 27;11(48):3561-3.
Eighty per cent of men with hyperprolactinaemia are impotent. Sexual deficiency, which for a long time is the only sign of the disease, is partly due to inhibition of testosterone secretion by high prolactin levels but also, probably, to reduced conversion of testosterone to dihydrotestosterone and, perhaps, to a direct effect of prolactin on the neurotransmitters involved in sexual activity. Eighty per cent of women with hyperprolactinaemia have reduced sexual drive and inability to reach orgasm; the underlying mechanisms are as yet unknown. In women, however, the initial symptoms are menstrual disorders. Most sexual disorders in both sexes regress after return to normal of plasma prolactin levels.
高催乳素血症患者中80%存在阳痿。长期以来，性功能缺陷一直是该疾病的唯一症状，部分原因是高催乳素水平抑制了睾酮分泌，但也可能是由于睾酮向双氢睾酮的转化减少，或许还与催乳素对参与性活动的神经递质的直接作用有关。高催乳素血症女性中80%有性欲减退和无法达到性高潮的情况；其潜在机制尚不清楚。然而，女性的初始症状是月经紊乱。血浆催乳素水平恢复正常后，男女的大多数性功能障碍都会消退。
