Whitman S, Hermann B P, Black R B, Chhabria S
Psychol Med. 1982 Nov;12(4):843-53. doi: 10.1017/s003329170004914x.
Previous investigations have reported an increased rate of behavioural disorder in children with epilepsy. The role, if any, played by temporal lobe epilepsy (TLE) in predisposing to psychopathology is unclear. In order to evaluate the relationship between seizure type and psychopathology, 35 children with TLE were compared with 48 children with primary generalized epilepsies (GE) on standardized measures of social competence, aggression and overall behavioural disorder via analyses of covariance. Additionally, Pearson correlations were computed in order to evaluate the relationships between psychopathology and several seizure and subject variables. It was found that the presence of TLE per se bore no relationship to aggression, social competence or overall behavioural disorder. Some specific subject- and seizure-related variables were found to be associated with increased aggression and behavioural dysfunction in children with TLE and the interpretation of these findings are related to the larger epilepsy/psychopathology literature. Finally, an alternative approach for studying the precursors of behavioural disorder in epilepsy is suggested.
先前的调查报道称癫痫患儿出现行为障碍的几率有所增加。颞叶癫痫（TLE）在引发精神病理学方面（若有作用的话）所起的作用尚不清楚。为了评估癫痫发作类型与精神病理学之间的关系，通过协方差分析，对35名颞叶癫痫患儿与48名原发性全身性癫痫（GE）患儿在社交能力、攻击性及总体行为障碍的标准化测量指标上进行了比较。此外，还计算了皮尔逊相关性，以评估精神病理学与若干癫痫发作及受试者变量之间的关系。研究发现，颞叶癫痫本身与攻击性、社交能力或总体行为障碍并无关联。研究发现一些与受试者及癫痫发作相关的特定变量与颞叶癫痫患儿攻击性增加及行为功能障碍有关，对这些研究结果的解读与更广泛的癫痫/精神病理学文献相关。最后，提出了一种研究癫痫中行为障碍先兆的替代方法。
