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[神经昏迷和脑死亡中早期体感诱发电位和听觉诱发电位的相关方面]

[Aspects of early somatosensory and auditory evoked potentials in neurologic comas and brain death].

作者信息

Mauguière F, Grand C, Fischer C, Courjon J

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1982 Nov;12(3):280-5. doi: 10.1016/s0370-4475(82)80056-7.

Abstract

Following stimulation of the median nerve at the wrist, SEPs, BAEPs and EEG activity were recorded during the same session in 20 comatose patients (13 head injuries, 6 comas of vascular origin, 1 anoxic coma). Patients were classified according to clinical data. In traumatic comas with clinically preserved brain stem reflexes (5 patients), BAEPs were all present, with preserved cervical N14 and scalp recorded P15 SEPs; the parietal N20 SEP was either present on both sides or unilaterally absent in case of hemispheric, possibly EEG silent, traumatic lesion. In comas with a reactive EEG and absent brain stem reflexes (8 patients), N14 and P15 SEPs were present when the parietal N20 component was absent on both sides. In these patients various aspects of BAEPs were observed, but in most cases (7 out of 8) either the BAEPs were completely absent or only peaks I or I and II were present. In brain-dead patients (7 cases) the cervical N14 was recorded in all cases, the P15 SEP was inconstant and the parietal N20 component was constantly abolished on both sides; in most cases (5 out of 7) all the BAEPs were absent. The practical use of evoked responses for the survey of comatose patients is discussed.

摘要

在20例昏迷患者(13例头部受伤、6例血管源性昏迷、1例缺氧性昏迷)中,于腕部刺激正中神经后,在同一次检查中记录了体感诱发电位(SEPs)、脑干听觉诱发电位(BAEPs)和脑电图(EEG)活动。根据临床资料对患者进行分类。在临床上脑干反射保留的创伤性昏迷患者(5例)中,所有患者均有BAEPs,颈段N14和头皮记录的P15 SEPs保留;顶叶N20 SEP双侧均存在或在半球性、可能脑电图无活动的创伤性病变时单侧缺失。在脑电图有反应但脑干反射消失的昏迷患者(8例)中,当双侧顶叶N20成分缺失时,N14和P15 SEPs存在。在这些患者中观察到BAEPs的各种情况,但在大多数病例(8例中的7例)中,要么BAEPs完全缺失,要么仅存在波峰I或波峰I和II。在脑死亡患者(7例)中,所有病例均记录到颈段N14,P15 SEP不稳定,双侧顶叶N20成分持续消失;在大多数病例(7例中的5例)中,所有BAEPs均缺失。文中讨论了诱发电位在昏迷患者检查中的实际应用。

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