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[肺毛细血管容积受限,淡水浸泡后呼吸窘迫综合征的延迟后遗症]

[Restriction of pulmonary capillary volume, delayed sequelae of immersion in fresh water with respiratory distress syndrome].

作者信息

Domenighetti G, Genoni L, Buchser E, Leuenberger P

出版信息

Schweiz Med Wochenschr. 1982 Dec 11;112(50):1838-41.

PMID:7156967
Abstract

Lung mechanics and pulmonary gas exchange studies were performed 6 and 12 months after the accident on 2 survivors of adult respiratory distress syndrome (ARDS) following near drowning in fresh water. The patients (25 and 29 years of age) were nonsmokers and neither had a history of lung disease. Immersion lasted 10 and 20 minutes, and assisted ventilation 19 and 34 days, respectively. The results show that lung mechanics returned to normal within 6 months after the onset of ARDS. Conversely, the ratio of dead space to tidal volume was increased significantly at rest and during exercise, and the ratio of capillary volume to alveolar volume was decreased in both patients. It is concluded that ARDS following prolonged near drowning in cold water causes late abnormalities of gas exchange probably related to decreased pulmonary capillary volume.

摘要

在两名淡水溺水后发生成人呼吸窘迫综合征(ARDS)的幸存者事故发生6个月和12个月后,进行了肺力学和肺气体交换研究。患者(分别为25岁和29岁)不吸烟,均无肺部疾病史。溺水持续时间分别为10分钟和20分钟,辅助通气分别为19天和34天。结果显示,ARDS发病后6个月内肺力学恢复正常。相反,两名患者在静息和运动时死腔与潮气量之比均显著增加,毛细血管容积与肺泡容积之比均降低。结论是,长时间冷水溺水后发生的ARDS会导致气体交换后期异常,可能与肺毛细血管容积减少有关。

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