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[动物体内吸入的氮氧化物NO和NO₂的转化]

[Transformation of the inhaled nitrogen oxides NO and NO2 in animals].

作者信息

Bompart G, Bourbon P, Levy P, do Phuoc H

出版信息

Toxicol Eur Res. 1982 Jul;4(4):187-90.

PMID:7157362
Abstract

The authors have studied in the lungs and blood the time course evolution of nitrogen oxides (NO and NO2) administered by inhalation, in rabbits and guinea pigs. NO2 was rapidly oxidized into NO3-. The latter were eliminated within 24 h, the oxidation rate having been variable according to animal species. In presence of NO, the persistence of NO3- beyond 24 h indicates a retardation of the oxidation, NO having to pass previously by the NO2- step.

摘要

作者们在兔子和豚鼠身上研究了通过吸入给予的氮氧化物(NO和NO₂)在肺和血液中的时间进程演变。NO₂迅速氧化成NO₃⁻。后者在24小时内被清除,氧化速率因动物种类而异。在有NO存在的情况下,NO₃⁻在24小时后仍持续存在,这表明氧化过程有所延迟,因为NO必须先经过NO₂⁻这一步骤。

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