Caddy B, Idowu O R, Stuart J F
Ther Drug Monit. 1982;4(4):389-95. doi: 10.1097/00007691-198212000-00010.
A reverse phase high pressure liquid chromatographic method has been developed for the analysis of 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) levels present in body fluids. A value obtained for the plasma half-life for a single patient indicates that this may be larger than hitherto expected.
已开发出一种反相高压液相色谱法,用于分析体液中1-(2-氯乙基)-3-(4-反式甲基环己基)-1-亚硝基脲(甲基环己亚硝脲)的含量。一位患者的血浆半衰期测定值表明,该半衰期可能比迄今预期的要长。