[Gastrin level in the blood serum fasting and after food intake in peptic ulcer and chronic gastritis with secretory failure].

Radioimmunoassay was used to determine the blood gastrin content in 45 patients and 14 healthy individuals. Examination was performed on an empty stomach and 20 and 40 minutes after trial breakfast. It was established that after the trial breakfast (35 g protein, 50 g fat, and 70 g carbohydrate) the greatest increment in the gastrin content, as compared to normal, was recorded in increased acid-forming gastric function (peptic ulcer with ulcer site in the duodenum). In patients with decreased acid production (peptic ulcer with ulcer site in the stomach, chronic gastritis with secretory failure), the gastrin content after the trial breakfast was lower than in healthy individuals and in duodenal ulcer patients.