Levitina M V
Zh Evol Biokhim Fiziol. 1982 Nov-Dec;18(6):573-7.
The content of cerebrosides and sulfocerebrosides has been determined in the whole brain, in the gray and white matter of the cerebral hemispheres of the macaque. Fatty acid composition and long chain bases of these sphingolipids in the whole brain were also investigated. The species studied belongs to the order of higher primates, the family of lower Old World monkeys. In the whole brain, rather high content of both sphingolipids was found, the cerebral white matter being the richer. Cerebrosides with hydroxy acids predominate in the whole brain, in the white and gray matter. Cerebrosides of the whole brain contain mainly palmitic and stearic acids and relatively small amounts of C24 normal fatty acids. In sulfocerebrosides, the proportion of palmitic and stearic acids is lower and that of C24 normal fatty acids--larger, as compared to cerebrosides. In both sphingolipids, the content of saturated hydroxy acids, mainly cerebronic acid, is rather high. Among the long chain bases, only sphingenine and sphinganine were detected the former being predominant. Sphingolipids from the brain of the macaque were compared to these from the human brain.
已测定猕猴大脑半球灰质和白质以及全脑中脑苷脂和硫脑苷脂的含量。还研究了全脑中这些鞘脂的脂肪酸组成和长链碱。所研究的物种属于高等灵长目、旧大陆猴科。在全脑中，发现这两种鞘脂的含量都相当高，大脑白质中含量更高。在全脑、白质和灰质中，含羟基酸的脑苷脂占主导。全脑的脑苷脂主要含有棕榈酸和硬脂酸，以及相对少量的C24正常脂肪酸。与脑苷脂相比，硫脑苷脂中棕榈酸和硬脂酸的比例较低，C24正常脂肪酸的比例较高。在这两种鞘脂中，饱和羟基酸（主要是脑胺酸）的含量相当高。在长链碱中，仅检测到鞘氨醇和二氢鞘氨醇，前者占主导。将猕猴大脑中的鞘脂与人脑鞘脂进行了比较。
