Bodson A, Becquevort P, Dwelshauvers J, Demol H, Michel L, Alexandre G P, Vanderbeck L
Ann Endocrinol (Paris). 1982 Jul-Sep;43(4):299-300.
This report concerns the history of a portugesian family including one case of MEN II a (female, born 1932, presenting medullary carcinoma of the thyroid--MCT--, hyperparathyroidism and suspected pheochomocytoma), and three others with MCT alone or in association with pheochromocytoma. The diagnosis of MCT has been made possible investigating six members of the kindred by use of IR - calcitonin measurements and pentagastrin injection. This provocative screening test is also of interest to follow operated patients.
本报告涉及一个葡萄牙家族的病史,其中包括1例IIa型多发性内分泌腺瘤病(女性,生于1932年,患有甲状腺髓样癌——MCT——、甲状旁腺功能亢进和疑似嗜铬细胞瘤),以及另外3例单独患有MCT或合并嗜铬细胞瘤的患者。通过对该家族6名成员进行降钙素免疫反应测定和注射五肽胃泌素,得以诊断MCT。这种激发性筛查试验对于随访接受手术的患者也很有意义。