Verdejo París J, González-Hermosillo J A, Díaz del Río A, Cárdenas Loaeza M
Arch Inst Cardiol Mex. 1982 Nov-Dec;52(6):487-94.
Seventeen patients with diagnosis of acute myocardial infarction with right ventricular extension were studied. All of them had evidence of contractile impairment of the right ventricle as shown by elevated filling pressure of the right ventricle, low systolic pulmonary pressure and low left ventricular filling pressure and cardiac output. These patients were treated with fluid infusion into the pulmonary artery besides other treatment measures for myocardial infarction in order to improve the filling pressure of the left ventricle and the cardiac output without stressing the right ventricle. The results obtained with this approach, which was maintained for 22 hours, showed a significant improvement in the stroke work indices of both ventricles and also in the cardiac output with a decrease in peripheral resistence without ever loading the ventricles. We analyze the physiological basis for using this procedure and also the complications that can occur. Our results show that the infusion of fluid into the pulmonary artery improves the hemodynamic situation of these patients and protects a damaged right ventricle.
对17例诊断为急性心肌梗死伴右心室扩展的患者进行了研究。所有患者均有右心室收缩功能受损的证据,表现为右心室充盈压升高、收缩期肺动脉压降低、左心室充盈压降低及心输出量降低。除了针对心肌梗死的其他治疗措施外,这些患者还接受了经肺动脉输液治疗,以提高左心室充盈压和心输出量,同时不给右心室增加负担。这种方法持续了22小时,结果显示,两个心室的每搏功指数和心输出量均有显著改善,外周阻力降低,且未增加心室负荷。我们分析了采用该方法的生理基础以及可能出现的并发症。我们的结果表明,经肺动脉输液可改善这些患者的血流动力学状况,并保护受损的右心室。