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单侧与双侧电休克治疗的比较:选择性记忆损害的证据

Comparison of unilateral and bilateral ECT: evidence for selective memory impairment.

作者信息

Fromm-Auch D

出版信息

Br J Psychiatry. 1982 Dec;141:608-13. doi: 10.1192/bjp.141.6.608.

DOI:10.1192/bjp.141.6.608
PMID:7159808
Abstract

Review of studies from the past 16 years employing quantitative measurement of memory functions before and after ECT revealed the following trends: impairment of non-verbal memory functions after less than five unilateral non-dominant ECTs; improvement of non-verbal memory functions after five or more unilateral non-dominant ECTs; no change or improvement of verbal memory functions with unilateral non-dominant ECT; consistent impairment of verbal functions with unilateral dominant ECT, and impairment of both verbal and non-verbal functions with bilateral ECT. The relative lack of impairment in memory functions with unilateral non-dominant ECT is consistent with the theory of asymmetrical hemispheric disorganization in affective disorders, and supports the choice of unilateral non-dominant ECT over bilateral or unilateral dominant ECT in the treatment of depression.

摘要

对过去16年中采用定量测量ECT前后记忆功能的研究进行回顾,发现以下趋势:少于5次单侧非优势ECT后非言语记忆功能受损;5次或更多次单侧非优势ECT后非言语记忆功能改善;单侧非优势ECT后言语记忆功能无变化或改善;单侧优势ECT导致言语功能持续受损,双侧ECT导致言语和非言语功能均受损。单侧非优势ECT在记忆功能方面相对缺乏损害,这与情感障碍中半球不对称性紊乱理论一致,并支持在抑郁症治疗中选择单侧非优势ECT而非双侧或单侧优势ECT。

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引用本文的文献

1
The electroconvulsive therapy controversy: evidence and ethics.电休克治疗争议:证据与伦理
Neuropsychol Rev. 2003 Dec;13(4):199-219. doi: 10.1023/b:nerv.0000009484.76564.58.
2
Neuropsychology and psychopathology: a progress report.
Neuropsychol Rev. 1990 Jun;1(2):103-23. doi: 10.1007/BF01108713.