Wiśniewska I E, Gawlik Z
Folia Histochem Cytochem (Krakow). 1982;20(3-4):157-62.
The doxycycline effect on the activity of alkaline phosphatase in the brush border of the convoluted renal tubules in rat was examined, using the interferometric technique. On the basis of measurements taken, the antibiotic was shown to cause a statistically significant fall of the alkaline phosphatase activity and the enzyme activity was found to decrease with consecutive doses of the drug under investigation.
采用干涉测量技术，研究了强力霉素对大鼠肾曲小管刷状缘碱性磷酸酶活性的影响。根据所测得的数据，该抗生素可使碱性磷酸酶活性在统计学上显著下降，且在所研究药物连续给药时，酶活性降低。
