Portillo M L, de González C M, Sangines J B, Zapata G S
Int Surg. 1982 Oct-Dec;67(4):329-33.
Pineal region tumors, which comprise 0.4% to 1% of intracranial neoplasms, are classified into four groups: teratomas, pinealomas; glial forms; and cysts. Clinically, they produce hydrocephalus due to the obstruction of the cerebral duct; lesions of the vegetative centers of the hypothalamus; invasion of the quadrigeminal tubercles, producing a symptomatology which varies according to the region affected and occasionally, precocious puberty and diabetes insipidus. Cases of ectopic pinealoma in the hypophyseal region are rarely seen; germinoma is the most frequent. Microscopically, two cell populations can be observed: lymphocytes and large germinal cells. The ultrastructural study reports five cell types. We consider the simple skull x-ray, cerebral angiography, Conray ventriculography and CAT Scan of utmost importance. Over the last six years, we have observed five germinomas and one pinealoblastoma. Five patients were treated surgically with subsequent radiation therapy. Two died; three are under control at the out-patient clinic and recuperating well. One patients died completion of tests.
松果体区肿瘤占颅内肿瘤的0.4%至1%，分为四组：畸胎瘤、松果体瘤；神经胶质型；以及囊肿。临床上，它们会因脑导水管阻塞导致脑积水；下丘脑自主神经中枢受损；四叠体结节受侵，产生的症状因受累区域而异，偶尔还会出现性早熟和尿崩症。垂体区异位松果体瘤病例罕见；生殖细胞瘤最为常见。显微镜下可观察到两种细胞群：淋巴细胞和大的生发细胞。超微结构研究报告有五种细胞类型。我们认为简单的颅骨X线检查、脑血管造影、Conray脑室造影和计算机断层扫描极为重要。在过去六年中，我们观察到五例生殖细胞瘤和一例松果体母细胞瘤。五名患者接受了手术治疗，随后进行了放射治疗。两名患者死亡；三名患者在门诊得到控制，恢复良好。一名患者在检查完成后死亡。
