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出生后营养不良及营养康复后大鼠脑内的儿茶酚胺

Catecholamines in rat brain following postnatal undernutrition and nutritional rehabilitation.

作者信息

Wiggins R C, Fuller G N, Seifert W E, Butler I J, Gottesfeld Z

出版信息

J Neurosci Res. 1982;8(4):651-6. doi: 10.1002/jnr.490080409.

Abstract

Norepinephrine and dopamine were examined in 19 discrete brain areas from the telencephalon, diencephalon, and mesencephalon of nutritionally rehabilitated adult rats following postnatal undernutrition from birth through 21 days of age. Following rehabilitation, catecholamine levels were not significantly different from control values in any of the areas examined. Catecholamine concentrations in young, undernourished rats are generally elevated (either from stress or from nutritional insufficiency). Data presented here show that whichever case is true, the early effect of undernourishment is transient and that normal values are restored by nutritional rehabilitation.

摘要

对出生后至21日龄处于营养不足状态、成年后营养恢复正常的大鼠,检测其端脑、间脑和中脑19个不同脑区的去甲肾上腺素和多巴胺。营养恢复后,所检测的任何脑区中儿茶酚胺水平与对照值均无显著差异。幼年营养不良大鼠的儿茶酚胺浓度通常会升高(原因可能是应激或营养不足)。此处给出的数据表明,无论哪种情况属实,营养不良的早期影响都是短暂的,营养恢复可使各项指标恢复至正常水平。

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