Zirm M
Klin Monbl Augenheilkd. 1982 Nov;181(5):425-8. doi: 10.1055/s-2008-1055266.
Healon, a product of Hyaluronic acid which has recently become available, has been used in anterior segment surgery. Despite the fact that optimistic results have been published the authors' aim was to evaluate the use of Healon in animal experiments as well as in clinical surgery. The following five questions were asked: (1) Is it possible to destroy the gel-like structure of Healon by ultrasound? (2) Is it possible to make Healon visible intraocularly by staining methods? (3) Is the protection of corneal endothelial cells by Healon demonstrable? (4) Does the use of Healon cause an increase in intraocular pressure after surgery? (5) Is the use of Healon in ophthalmic surgery an advantage? The results showed that with the exception of question 1, all the above mentioned questions can be answered.
喜辽妥(Healon)是一种最近才上市的透明质酸产品,已被用于眼前节手术。尽管已经发表了乐观的结果,但作者的目的是评估喜辽妥在动物实验以及临床手术中的应用。提出了以下五个问题:(1)是否可以通过超声破坏喜辽妥的凝胶状结构?(2)是否可以通过染色方法使喜辽妥在眼内可见?(3)喜辽妥对角膜内皮细胞的保护作用是否可证实?(4)使用喜辽妥是否会导致术后眼压升高?(5)在眼科手术中使用喜辽妥是否具有优势?结果表明,除问题1外,上述所有问题都可以得到答案。