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[硫胺素缺乏对胃盐酸分泌的影响]

[Effect of thiamine deficiency in hydrochloric acid secretion in the stomach].

作者信息

Levin L G, Mal'tsev G Iu, Gapparov M M

出版信息

Vopr Pitan. 1978 Sep-Oct(5):36-40.

PMID:716330
Abstract

The effect of the thiamine deficiency on the H+ secretion in an isolated gastric mucosa and also on the functional properties of the mitochondria was investigated. The thiamine deficiency was called forth through introduction of oxythiamine or by exclusion of thiamine from the ration. It is shown that the thiamine deficiency in an isolated gastric mucosa of the frog produced inhibition of the H+ secretion and in the gastric mitochondria of rats--a higher activity of succinate-dehydrogenase and a diminution of the exogenous cytochrome oxidation rate.

摘要

研究了硫胺素缺乏对离体胃黏膜H⁺分泌以及线粒体功能特性的影响。通过引入氧硫胺素或从日粮中排除硫胺素引发硫胺素缺乏。结果表明,青蛙离体胃黏膜中的硫胺素缺乏会抑制H⁺分泌,而大鼠胃线粒体中的硫胺素缺乏则会使琥珀酸脱氢酶活性升高,外源细胞色素氧化速率降低。

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