Frieder B, Allweis C
Physiol Behav. 1982 Dec;29(6):1059-64. doi: 10.1016/0031-9384(82)90298-0.
Rats rendered hypoxic by brief exposure to N2 after learning an avoidance response go into convulsions and subsequently become amnestic. Overt convulsions can be avoided whilst yet producing delayed post-hypoxic transient amnesia (DPHTA) by using 2% O2 in N2 in place of pure N2. The experiments reported here show that with this gas mixture, the ECoG shows hardly any of the electrical activity associated with seizures which occurs with N2. It is concluded that electrical seizures are not associated with the mechanism responsible for DPHTA.
在学会回避反应后，通过短暂暴露于氮气而导致缺氧的大鼠会发生惊厥，随后出现失忆。通过在氮气中使用2%的氧气代替纯氮气，可以避免明显的惊厥，同时又能产生延迟性缺氧后短暂失忆（DPHTA）。本文报道的实验表明，使用这种气体混合物时，脑电图几乎没有显示出与氮气引起的癫痫发作相关的任何电活动。得出的结论是，癫痫性电发作与DPHTA的发病机制无关。
