[Placental maturation disorders in relation to the quality of metabolic control during pregnancy in insulin-dependent and gestational diabetes].

In 1969/70 and 1979/80, 100 placentas each of diabetics were morphologically examined. The findings obtained were evaluated against the background of metabolic monitoring and typical phenomena of perinatal morbidity. The studies were conducted for the purpose of finding out the extent to which maintenance of normal glycaemic metabolism throughout pregnancy could affect the severity of diabetic disorders of placental maturation. Medium to severe placental maturation disorders were found to be closely correlated with quality of metabolic control (P less than 0.01). The findings thus obtained have produced evidence to the effect that maintenance of normal glycaemic metabolism throughout pregnancy would be of favourable impact not only upon perinatal mortality and morbidity. It would also cause significant reduction of placental maturation disorders.