Kleinebrecht J, Selow J, Winkler W
Anat Anz. 1982;152(4):313-24.
Homozygotes of the mouse mutant limb-deformity (ld) reveal a reduced fertility and a high mortality of newborns. Unilateral and bilateral aplasia of kidneys is very common. In unilateral aplasia the right side is affected most, with no sex preference. All extremities show aplasias and synostoses, with 22 malformation types in the forelimbs and 8 types in the hindlimbs. Primary and secondary fusions of limb elements are found.
小鼠突变体肢体畸形(ld)的纯合子表现出生育力降低和新生仔鼠死亡率高。单侧和双侧肾发育不全非常常见。在单侧肾发育不全中,右侧受影响最为严重,无性别偏好。所有四肢均出现发育不全和关节融合,前肢有22种畸形类型,后肢有8种类型。发现了肢体元件的原发性和继发性融合。