Al-Izzi S A, Maxie M G
Am J Vet Res. 1982 Dec;43(12):2244-7.
An IV injection of formalin-killed Corynebacterium parvum in calves did not cause a marked increase in the number of bone marrow macrophage colonies or peripheral blood monocytes, granulocytes, or lymphocytes. In treated calves, the spleen increased in weight and there were macrophage infiltrations in liver, lungs, spleen, and lymph nodes. Lymphoid hyperplasia was observed in bronchial-associated lymphoid tissue, cortical areas of the thymus, and in primary and secondary follicles and the paracortical area of lymph nodes.
给小牛静脉注射经福尔马林灭活的微小棒状杆菌，并未导致骨髓巨噬细胞集落数量或外周血单核细胞、粒细胞或淋巴细胞数量显著增加。在接受治疗的小牛中，脾脏重量增加，肝脏、肺、脾脏和淋巴结出现巨噬细胞浸润。在支气管相关淋巴组织、胸腺皮质区域以及淋巴结的初级和次级滤泡及副皮质区域观察到淋巴样增生。
