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[血流的时间性紊乱对肌间神经丛神经元结构的影响]

[Effect of temporal disturbance of the blood flow on the structure of neurons of the myenteric plexus].

作者信息

Liubaev V A

出版信息

Arkh Anat Gistol Embriol. 1982 Nov;83(11):70-6.

PMID:7165520
Abstract

The dynamics of changes occurring in the myenteric plexus neurons have been followed in 230 mature cats from the first step up to the 120th day after 1-, 2.5-, 4-, 6-, 8-hour's disturbance in the arterial and venous blood circulation using Bielschowsky--Gros, Nissl and Nachlas techniques. Depending on duration of the ischemia and the postischemic period, various amount of unchanged neurons and neurons having certain reactive and destructive changes have been revealed. During all the periods of the investigation, certain differences are noted in the reaction both of all the ganglia and single neurons within one ganglion. Some neurons demonstrate certain resistivity to the prolonged disturbance in the blood flow. By means of the polarography method, the dynamics of changes in the oxygen strain in tissues of the experimental area of the small intestine after the arterial and mixed ischemia have been studied. An elevated oxygen strain has been revealed in the tissues under conditions of venous congestion and an attempt has been made to explain this effect.

摘要

运用 Bielschowsky - Gros、尼氏染色法和纳赫拉斯技术,对230只成年猫在动脉和静脉血液循环分别受到1、2.5、4、6、8小时干扰后的第1天至第120天,观察其肌间神经丛神经元发生的变化动态。根据缺血持续时间和缺血后时期,发现了不同数量的未改变神经元以及具有某些反应性和破坏性变化的神经元。在整个研究期间,观察到所有神经节以及单个神经节内单个神经元的反应存在一定差异。一些神经元对血流的长期干扰表现出一定的抵抗力。通过极谱法,研究了动脉缺血和混合缺血后小肠实验区域组织中氧张力的变化动态。发现在静脉淤血情况下组织中的氧张力升高,并尝试对这种效应作出解释。

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