Gigante G E, Varrassi G
Boll Soc Ital Biol Sper. 1982 Dec 15;58(23):1596-1601.
Bromine concentration in the blood of seven patients anesthetized with Halothane are determined at different time before, during and after anesthetic induction. X.R.F. technique was employed in the analytical determinations using a new background correction method which assume a linear relationship between primary Compton in matrix of monocromathic source radiation and background counts. Mini mun Detectable Limits are of - 5 p.p.m. and accuracy of 3% at 20-30 p.p.m. concentration. 24 h after anesthesia Bromine levels are always significantly high (-20 p.p.m.); the clinical importance of these data are discussed.
测定了七名接受氟烷麻醉的患者在麻醉诱导前、诱导期间和诱导后的不同时间点血液中的溴浓度。在分析测定中采用了X射线荧光(X.R.F.)技术,使用一种新的背景校正方法,该方法假定单色源辐射基质中的初级康普顿散射与背景计数之间存在线性关系。最低检测限为-5 ppm,在浓度为20 - 30 ppm时准确度为3%。麻醉后24小时,溴水平始终显著升高(-20 ppm);讨论了这些数据的临床意义。