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淋巴结中的上皮性包涵体。诊断、组织发生及预后问题。

Epithelial inclusions in the lymph nodes. Diagnostic, histogenetic, and prognostic problems.

作者信息

Gricouroff G

出版信息

Diagn Gynecol Obstet. 1982 Winter;4(4):285-93.

PMID:7166115
Abstract

The capacity of epithelial cancer to invade the lymph nodes is a common notion. Adenopathy may, on rare occasions, be the first clinical sign of an unrecognized cancer. Exceptionally following the discovery in a lymph node of malignant-looking epithelial inclusions, a complete examination of the patient will reveal no primary tumor and the case will remain unexplained. Conversely, it may also happen that upon microscopic examination of the nodes which, for one reason or another, have been removed, benign-looking epithelial inclusions are discovered. In women, these are most often endometrial type glands; in men, they are usually thyroid follicles. The diagnostic, histogenetic, and prognostic problems raised by these various inclusions are, of course, different; however, their one point in common--the ectopic presence of epithelial tissue in a lymph node--and the controversy concerning the benign or malignant nature of certain inclusions, incite this comprehensive study.

摘要

上皮癌侵犯淋巴结的能力是一个普遍的概念。淋巴结病在极少数情况下可能是未被识别的癌症的首个临床症状。异常的是,在淋巴结中发现看似恶性的上皮包涵体后,对患者进行全面检查却未发现原发性肿瘤,该病例将一直无法解释。相反,也可能出现这样的情况,即在对因各种原因切除的淋巴结进行显微镜检查时,发现看似良性的上皮包涵体。在女性中,这些包涵体最常见的是子宫内膜样腺体;在男性中,它们通常是甲状腺滤泡。当然,这些不同的包涵体引发的诊断、组织发生学和预后问题是不同的;然而,它们的一个共同点——上皮组织在淋巴结中的异位存在——以及关于某些包涵体的良性或恶性性质的争议,促使了这项全面研究。

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