Evaluation of short stature in children.

Within a year 429 children referred for short stature have been evaluated. The age at consultation ranged from 5 months to 17 1/2 years. Healthy but small children came at 5 to 7 and 10 to 13 years, while those with different pathologies attended the clinic at all ages. The stature of 43% of the investigated children ranged within normal limits (till -2 SDS), while 57% had a small stature. 68% of the children could be considered healthy, 32% had different endocrine and nonendocrine diseases responsible for their growth retardation. Retarded bone age (greater than 2 SD below the mean) was observed in 65% of the significantly short but otherwise healthy children and in only 28% of the healthy children with heights above -2 SD. Extreme short stature was mainly associated with a recognized disease of chronic and genetic origin, low birthweight and malnutrition. The high incidence of hypopituitarism (15 patients) is due to the fact that this study was performed in an endocrine clinic.