Horner J M, Thorsson A V, Hintz R L
Pediatrics. 1978 Oct;62(4):529-34.
A retrospective study of 263 children referred for evaluation of short stature revealed that 149 (56.7%) had constitutional short stature (CSS). A typical pattern of growth was observed in these children. As exemplified by 12 children who had complete serial growth measurements, exaggerated growth deceleration first became apparent between 3 and 6 months of age, was greatest in the first two years of life, and resulted in these children falling more than 2 SDs below the mean for height by 3 years of age. After 3 years of age, the growth rate of these children with CSS was essentially the same as that of normal children, and they ran parallel to the growth curve though below the third percentile. The importance of serial measurements and the growth chart is emphasized, and recommendations are made for the evaluation of short stature or abnormal growth deceleration in the first three years of life. Awareness of this typical pattern of growth in children without disease may aid the pediatrician in his evaluation of short stature and allow for watchful waiting when results of screening tests are normal.
一项对263名因身材矮小前来评估的儿童的回顾性研究显示，149名（56.7%）患有体质性身材矮小（CSS）。在这些儿童中观察到了典型的生长模式。以12名有完整连续生长测量数据的儿童为例，生长减速加剧首先在3至6个月龄时变得明显，在生命的头两年最为显著，导致这些儿童在3岁时身高低于平均水平超过2个标准差。3岁以后，这些患有CSS的儿童的生长速度与正常儿童基本相同，他们的生长曲线虽低于第三百分位数但与之平行。强调了连续测量和生长图表的重要性，并对生命头三年身材矮小或生长减速异常的评估提出了建议。认识到无疾病儿童的这种典型生长模式可能有助于儿科医生评估身材矮小，并在筛查测试结果正常时进行观察等待。
