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大鼠外翻肠囊对铝的吸收

Aluminum absorption in the rat everted gut sac.

作者信息

Feinroth M, Feinroth M V, Berlyne G M

出版信息

Miner Electrolyte Metab. 1982 Jul;8(1):29-35.

PMID:7167130
Abstract

Intestinal absorption of aluminum was studied in rat everted gut sacs. Aluminum transport and aluminum uptake in the jejunum initially rose with increasing bath aluminum concentration, but reached a plateau with high bath aluminum concentrations. The aluminum transport was inhibited by dinitrophenol, absence of glucose, and a temperature of 4 degrees C. There was no change with acute renal failure, chronic renal failure, parathyroidectomy, or parathyroid hormone injection. The aluminum absorption from the rat jejunum appears to involve an energy-dependent, carrier-mediated mechanism.

摘要

在大鼠外翻肠囊中研究了铝的肠道吸收情况。空肠中铝的转运和摄取最初随浴液中铝浓度的增加而升高,但在高浴液铝浓度时达到平台期。铝的转运受到二硝基苯酚、无葡萄糖以及4℃温度的抑制。急性肾衰竭、慢性肾衰竭、甲状旁腺切除术或注射甲状旁腺激素对此均无影响。大鼠空肠对铝的吸收似乎涉及一种能量依赖的、载体介导的机制。

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