Abstract
The porphyrias are a result of disordered heme metabolism. The sequelae are related to the accumulation of precursors and/or their metabolism. Induced drug metabolism can lead to acute attacks and may result in fatalities. Careful selection of intravenous agents, absolute avoidance of barbiturates, and use of inhalation agents can enable the anesthetist to administer safe anesthesia to these endangered patients.
摘要
卟啉症是血红素代谢紊乱的结果。其后遗症与前体物质的积累和/或它们的代谢有关。药物诱导的代谢可导致急性发作，并可能导致死亡。谨慎选择静脉用药、绝对避免使用巴比妥类药物以及使用吸入性药物，可使麻醉医生为这些高危患者实施安全的麻醉。
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10
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