Bjerre-Jepsen K, Kristensen P, Horn A, Rydahl K
Acta Chir Scand. 1982;148(7):557-61.
Intraoperative autotransfusion (IAT) was proposed in 1818 by Blundell. In 1968 Klebanoff introduced the modern IAT system (Bently ATS-200) which can suck blood from the operative field and infuse up to 900 ml/min into the patient again. Ten patients in this series were autotransfused a median of 2275 ml blood during aortoiliac surgery for occlusive arterial disease. Blood samples taken before, during and after surgery showed no significant changes attributable to IAT, except for a minor decrease in the platelets. Total heparinization for elective vascular surgery and citrate (ACD or CPD) for emergencies is recommended. IAT was found safe, easy to operate, efficient in handling large quantities of blood and relatively inexpensive. Furthermore autotransfused blood--in contrast to bank blood--has a normal content of platelets and labile clotting factors.
术中自体输血（IAT）由布伦德尔于1818年提出。1968年，克莱巴诺夫引入了现代IAT系统（本特利ATS - 200），该系统可从手术区域吸取血液，并以高达每分钟900毫升的速度再次输回患者体内。在本系列研究中，10例患者在因闭塞性动脉疾病接受主髂动脉手术期间，自体输血的中位数为2275毫升。术前、术中和术后采集的血样显示，除血小板略有减少外，未发现因IAT导致的显著变化。对于择期血管手术建议进行全身肝素化，对于急诊手术建议使用枸橼酸盐（ACD或CPD）。研究发现IAT安全、易于操作、处理大量血液效率高且成本相对较低。此外，与库存血相比，自体输血的血液中血小板和不稳定凝血因子含量正常。
