Zhang T X, Rohlicek C V, Polosa C
J Auton Nerv Syst. 1982 Nov;6(3):381-9. doi: 10.1016/0165-1838(82)90009-1.
The relation between end-tidal (ET) pCO2 and firing rate of sympathetic preganglionic neurons (SPN) of the cervical sympathetic trunk was studied during hyperoxic hypercapnia in acute C1 or C4 spinal cats. The cats were under barbiturate anesthesia or anemically decerebrate. The firing rate of the majority of the tonically active strands (18/22) increased in hypercapnia and showed a continuous relation to ET pCO2 within the range studied. The firing rate of the remaining 4 strands was unaffected. The maximum increase in firing rate of the responsive strands was 3.7 times the control value on average (range 2.5-14.0). Recruitment of units which were silent in control conditions also occurred. These data demonstrate the existence of a spinal mechanism responsible for excitation of SPN during systemic hypercapnia.
在急性C1或C4脊髓猫的高氧高碳酸血症期间，研究了颈交感干的呼气末（ET）pCO2与交感神经节前神经元（SPN）放电频率之间的关系。这些猫处于巴比妥类麻醉或贫血性去大脑状态。在高碳酸血症时，大多数紧张性活动的神经束（18/22）的放电频率增加，并且在所研究的范围内与ET pCO2呈连续关系。其余4条神经束的放电频率未受影响。反应性神经束放电频率的最大平均增加量为对照值的3.7倍（范围为2.5 - 14.0）。在对照条件下沉默的单位也出现了募集现象。这些数据表明存在一种脊髓机制，负责在全身性高碳酸血症期间激发SPN。
