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[儿童原发性非手术治疗膀胱输尿管反流的病程。附44例报告]

[Course of primary nonoperated vesicorenal reflux in children. Apropos of 44 cases].

作者信息

Averous M, Arbieu S, Guiter J, Grasset D

出版信息

J Urol (Paris). 1982;88(9):587-90.

PMID:7169546
Abstract

From a series of 600 cases of reflux seen over 12 years, the authors chose a group of 44 children aged between 3 and 11 who had not been operated for their reflux. The period of follow-up ranged from 1 to 10 years. Treatment consisted of massive antibiotic therapy for the severe episodes of infection and maintenance treatments for more than six months in a great many cases. For this group of 44 children with 60 refluxing ureters, the results were: --a disappearance of infection in 82% of cases, --a disappearance of the reflux in 70% of cases, even including type III reflux. 4 children were lost to follow-up, and 5 had to be operated secondarily. The authors reserve this trial of medical treatment to reflux in the small child, intermittent reflux, reflux with no or only minor involvement of the upper urinary tract on I.V.P. and finally, reflux which causes infections particularly sensitive to medical treatment in the presence of a cooperative family. With the aim of reducing the irradiation to a minimum, the authors performed follow-up urography with a single 15 min film every two years and annual isotope cystography. The authors discuss the possibilities of extending this medical approach for the future.

摘要

在12年间观察到的600例反流病例中,作者选取了44名年龄在3至11岁之间、尚未因反流接受手术的儿童。随访时间为1至10年。治疗方法包括对严重感染发作进行大量抗生素治疗,在许多情况下进行超过6个月的维持治疗。对于这组44名患有60条反流输尿管的儿童,结果如下:——82%的病例感染消失;——70%的病例反流消失,甚至包括III型反流。4名儿童失访,5名儿童不得不二次手术。作者将这种药物治疗试验保留给小儿反流、间歇性反流、静脉肾盂造影显示上尿路无或仅有轻微受累的反流,以及最后在有合作家庭的情况下对药物治疗特别敏感的引起感染的反流。为了将辐射降至最低,作者每两年进行一次单次15分钟的尿路造影随访,并每年进行同位素膀胱造影。作者讨论了未来扩展这种医学方法的可能性。

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