Aladjem M, Boichis H, Hertz M, Herzfeld S, Raviv U
Pediatrics. 1980 Jan;65(1):78-80.
A group of 121 children with vesicoureteric reflux (VUR) grades 1 to 3 managed conservatively were followed-up for a period of six to ten years. In the majority of patients VUR grades 1 and 2 disappeared spontaneously. Prognosis was less favorable in those who were seen initially with grade 3 VUR. A statistically significant higher incidence of reflux disappearance was observed in children who were seen before 4 years of age. In the majority of patients with paraureteric-vesicle diverticulum, reflux persisted. Reflux was more likely to disappear in children with lower incidence of urinary tract infection than in those with multiple infections.
对121名1至3级膀胱输尿管反流（VUR）且采用保守治疗的儿童进行了为期6至10年的随访。大多数1级和2级VUR患者的反流自发消失。最初诊断为3级VUR的患者预后较差。4岁前就诊的儿童反流消失的发生率在统计学上显著更高。在大多数输尿管旁膀胱憩室患者中，反流持续存在。与多次感染的儿童相比，尿路感染发生率较低的儿童反流更有可能消失。
