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离体心脏的机械性房室时间与房室传导时间的相关性

The mechanical atrioventricular time of isolated hearts as a correlate of the atrioventricular conduction time.

作者信息

Güttler K, Klaus W, Sander W, Valenta U

出版信息

Adv Myocardiol. 1982;3:153-8. doi: 10.1007/978-1-4899-5561-6_16.

DOI:10.1007/978-1-4899-5561-6_16
PMID:7170435
Abstract

The time difference between onset of contraction in right atrium and left ventricle of isolated guinea pig hearts (mechanical AV time) was measured continuously by an impulse-triggered interval counter and taken as an equivalent of the electrophysiological AV conduction time derived from the epicardial ECG. Excellent correlation between these two parameters was established over a broad range of experimentally modified conduction times. The method was used to analyze the influence of electrical pacing, epinephrine, Ca2+ ions, and adenosine both on the AV conduction and on functional parameters of the hearts and revealed advantages in comparison to separate tests of single parameters in different experimental arrangements.

摘要

通过脉冲触发间隔计数器连续测量离体豚鼠心脏右心房和左心室收缩开始之间的时间差(机械性房室时间),并将其视为源自心外膜心电图的电生理房室传导时间的等效值。在广泛的实验性改变传导时间范围内,建立了这两个参数之间的良好相关性。该方法用于分析电起搏、肾上腺素、钙离子和腺苷对房室传导以及心脏功能参数的影响,与在不同实验设置中单独测试单个参数相比,显示出优势。

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