Cassuto J, Larsson P, Yao T, Jodal M, Thoren P, Andersson S, Lundgren O
Acta Physiol Scand. 1982 Dec;116(4):443-6. doi: 10.1111/j.1748-1716.1982.tb07164.x.
The effect on rate of cholera secretion in the small bowel of activation of the group III and A delta afferent fibres in the sciatic nerve was studied in rats. Activation of these fibres at 3 Hz for 60 min significantly diminished choleraic secretion from 121 +/- 29 to 25 +/- 9 microliters x min-1 x 100 cm-2 serosal surface (mean +/- SE; n = 9). The effect was apparent after the nerve stimulation. Stimulation of the sciatic nerve had no significant effect on choleraic fluid secretion after interrupting the autonomic nerves to the intestine, nor did it significantly alter net fluid transport in non-choleraic intestine with intact nervous supply. It is proposed that the observations may explain the clinical reports of an effect of acupuncture on cholera secretion.
在大鼠身上研究了坐骨神经中Ⅲ组和Aδ传入纤维的激活对小肠霍乱分泌速率的影响。以3Hz的频率激活这些纤维60分钟，可使霍乱分泌量从121±29显著减少至25±9微升·分钟⁻¹·100平方厘米浆膜表面（平均值±标准误；n = 9）。该效应在神经刺激后明显。在切断肠道自主神经后，刺激坐骨神经对霍乱液体分泌无显著影响，在神经供应完整的非霍乱肠道中，刺激坐骨神经也未显著改变液体净转运。有人提出，这些观察结果可能解释了针灸对霍乱分泌有影响的临床报告。
