Radde I C, Cifuentes R F, Chance G W
Adv Exp Med Biol. 1978;103:233-42. doi: 10.1007/978-1-4684-7758-0_26.
Five patient groups of VLBW infants with the same P-intake but varying Ca and Na intake were examined as to their urinary excretion of P and Na and on their renal clearance of P. The effect of increasing the Na intake from 1.5 to 3 mEq/kg/24 h on C(P) was also examined. In the control group of infants with an intake of 210 mg Ca and 80 mg P/kg/24 h, the C(P) was significantly correlated with postnatal, but not postconceptional age. A relatively low Ca intake of 100 mg/kg/24 h led to age-related values two to three times as high, whereas Ca supplementation to a total intake of 250 mg/kg/24 h decreased the C(P) significantly. A Ca intake of 175 mg/kg/24 h led to C(P) similar to those seen with one of 100 mg/kg/24 h. Changing the Na intake from 1,5 to 3 mEq/kg/24 h did not influence the C(P). There was no correlation between UP and UNa in any of the patient groups examined.
对五组极低出生体重儿进行了检查，这些患儿的磷摄入量相同，但钙和钠摄入量不同，检测了他们的磷和钠尿排泄量以及磷的肾脏清除率。还研究了钠摄入量从1.5增加到3 mEq/kg/24小时对磷清除率（C(P)）的影响。在摄入210 mg钙和80 mg磷/kg/24小时的婴儿对照组中，C(P)与出生后年龄显著相关，但与孕龄无关。相对较低的钙摄入量100 mg/kg/24小时导致与年龄相关的值高出两到三倍，而补充钙使总摄入量达到250 mg/kg/24小时时，C(P)显著降低。钙摄入量为175 mg/kg/24小时时，C(P)与100 mg/kg/24小时时的相似。将钠摄入量从1.5 mEq/kg/24小时改为3 mEq/kg/24小时对C(P)没有影响。在所检查的任何患者组中，尿磷（UP）和尿钠（UNa）之间均无相关性。
