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蛋氨酸亚砜及其他一些含硫氨基酸的氮节约效应。

The nitrogen-sparing effect of methionine sulphoxide and some other sulphur-containing amino acids.

作者信息

Njaa L R, Aksnes A

出版信息

Br J Nutr. 1982 Nov;48(3):565-70. doi: 10.1079/bjn19820141.

DOI:10.1079/bjn19820141
PMID:7171541
Abstract

The nitrogen-sparing effect of methionine, methionine sulphoxide, homocystine, cystine and choline was studied in rats by determining dialy N excretions during 5 d after changing from a high-protein diet to a protein-free diet, L-glutamic acid was used as a negative control. 2. L-, D- and DL-methionine were equally active in sparing N. L-methionine sulphoxide, DL-homocystine and L-cystine were as active as L-methionine. D-methionine sulphoxide was slightly less active than L-methionine sulphoxide. Choline hydrogen tartrate was not different from the negative control. 3. It is concluded that in short-term experiments cystine is the key substance in the N-sparing effect.

摘要

通过测定从高蛋白饮食改为无蛋白饮食后5天内的每日氮排泄量,研究了蛋氨酸、蛋氨酸亚砜、同型半胱氨酸、胱氨酸和胆碱对大鼠的氮节约作用。L-谷氨酸用作阴性对照。2. L-、D-和DL-蛋氨酸在节约氮方面具有同等活性。L-蛋氨酸亚砜、DL-同型半胱氨酸和L-胱氨酸与L-蛋氨酸活性相同。D-蛋氨酸亚砜的活性略低于L-蛋氨酸亚砜。酒石酸氢胆碱与阴性对照无差异。3. 得出结论,在短期实验中,胱氨酸是氮节约作用的关键物质。

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