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[实验性局灶性心肌炎和低氧性缺氧时大鼠组织中的泛醌和维生素E含量]

[Ubiquinone and vitamin E content in rat tissues in experimental focal myocarditis and hypoxic hypoxia].

作者信息

Donchenko G V, Kuz'menko I V, Koliadenko E V, Chagovets R V

出版信息

Biull Eksp Biol Med. 1982 Sep;94(9):36-8.

PMID:7171822
Abstract

The content of ubiquinone and vitamin E in liver, heart, kidney and muscle tissues has been found to vary in experimental focal myocarditis and acute hypoxic hypoxia. These compounds have been demonstrated to accumulate in myocardial mitochondria, which is likely to be related to both interstitial and inter-organ redistribution having a compensatory-adaptation importance. In the pathology under study, the myocardium demonstrates a greater intensity and more remarkable line of changes in the content of vitamin E and ubiquinone. It is suggested that these substances contribute to the increased body resistance to hypoxic exposures of varying genesis.

摘要

研究发现,在实验性局灶性心肌炎和急性低氧性缺氧状态下,肝脏、心脏、肾脏和肌肉组织中的泛醌和维生素E含量会发生变化。这些化合物已被证明会在心肌线粒体中蓄积,这可能与具有代偿适应重要性的间质和器官间再分布有关。在所研究的病理状态下,心肌中维生素E和泛醌含量的变化强度更大、变化趋势更显著。提示这些物质有助于增强机体对不同成因低氧暴露的抵抗力。

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