Törnqvist A, Ekelund G, Leandoer L
Br J Surg. 1982 Dec;69(12):725-8. doi: 10.1002/bjs.1800691213.
A previous study undertaken by this department showed follow-up to be of little value in tracing curable recurrences in patients with colorectal cancer who had curative operations. The aim of the present investigation was to determine if more intensified follow-up would result in earlier diagnosis of recurrences and thus lead to earlier and more effective treatment. Altogether 599 patients with colorectal cancer were treated between 1973 and 1977. The 363 (61 per cent) patients who were operated upon for cure entered the study and were followed up until December 1979. The same incidence of recurrence was seen in both series, but, with the more detailed protocol, they were more frequently detected before symptoms developed. However, the rate of curative reoperation for recurrence was not changed and only few patients survived after such reoperations. The conclusion is that the previous protocol is as efficient as the detailed one while no effective treatment of disseminated disease exists.
该部门之前进行的一项研究表明，对于接受过根治性手术的结直肠癌患者，随访对于追踪可治愈的复发情况几乎没有价值。本研究的目的是确定更强化的随访是否会导致复发的更早诊断，从而实现更早且更有效的治疗。1973年至1977年间，共有599例结直肠癌患者接受了治疗。其中363例（61%）接受了根治性手术的患者进入研究，并随访至1979年12月。两个系列中复发的发生率相同，但采用更详细的方案时，复发在症状出现前被更频繁地检测到。然而，复发后的根治性再次手术率并未改变，且此类再次手术后仅有少数患者存活。结论是，在不存在针对播散性疾病的有效治疗方法时，之前的方案与详细方案一样有效。
