Illes P, Meier C, Starke K
Brain Res. 1982 Nov 11;251(1):192-5. doi: 10.1016/0006-8993(82)91292-6.
The interaction between calcium and magnesium or normorphine was studied on the electrically evoked outflow of previously incorporated [3H]noradrenaline in the isolated mouse vas deferens. The stimulation-evoked outflow of [3H]noradrenaline increased with increasing concentrations of Ca2+ ions in the medium. Mg2+ counteracted the effect of Ca2+ in a manner compatible with competitive antagonism. In contrast, normorphine interfered with the effect of Ca2+ non-competitively, thus suggesting that its mode of action differed from that of Mg2+.
在离体小鼠输精管中，研究了钙与镁或去甲吗啡之间对预先摄取的[3H]去甲肾上腺素电诱发释放的相互作用。随着培养基中Ca2+离子浓度的增加，刺激诱发的[3H]去甲肾上腺素释放量增加。Mg2+以与竞争性拮抗作用相符的方式抵消了Ca2+的作用。相比之下，去甲吗啡非竞争性地干扰了Ca2+的作用，因此表明其作用方式与Mg2+不同。
